Archive for the ‘Pain Killer’ category

Aspirin’s ability to interfere with the synthesis of prostaglandins accounts for its effectiveness as an:?

December 16th, 2010
Jenn S asked:


(a) ant-clotting agent
(b) analgesic
(c) antipyretic
(d) 2 of these are correct

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How Food Addiction is Similar to Drug Addiction

December 13th, 2010
Patrick Meninga asked:


Some people are indeed addicted to food and in some cases they treat eating almost like a drug. Those who are really addicted to food can develop all sorts of problems in their life as a direct result of eating too much, or eating unhealthy foods.

One of the bigger hurdles with eating addiction comes from the fact that the recovery strategy cannot really be complete abstinence from all food, like we would do for drugs or alcohol. Instead of this, those who have food addiction have to learn moderation, something this is pretty much seen as an unlikely outcome when it comes to handling other types of addictions. We all have to live to eat…there is no abstinence-based option for food addiction recovery. This makes it trickier to recover from than some other types of addictions, where a person can abstain entirely, such as drugs, gambling, and so on.

In spite of this stark difference, food addiction is actually quite similar to drug addiction. This is because of the general underlying principle for which addicts tend to use drugs and alcohol or eat emotionally in an addictive way. In each of these instances, addicts are using either eating or chemical substances in order to deal with their emotions.

When someone with drug addiction has a rough day or becomes angered with a situation, they will generally resort to self medicating with their drug of choice in order to feel better about themselves. Similarly, a food addict will turn to certain comfort foods when they are upset about something in their life or feel stressed out. This is an example of emotional eating, and obviously this is a form of medicating that is very similar to how people use drugs or alcohol.

Food addicts can deliberately raise their consciousness and see when they are reaching for a bag of potato chips out of boredom or frustration, instead of to satisfy genuine hunger. Many people get bored and will simply much on things that they don’t really need. Others will munch on food simply out of habit, such as when they watch television.

In the same way, drug addicts take drugs for much the same motivations. Habits form slowly over time, and drug addicts might also try drugs out of sheer boredom also. The parallels here are pretty obvious and so it naturally follows that those who have an issue with eating addiction are really using food just like they would an addictive substance. They are self medicating for a number of different reasons by getting a small rush that comes from filling up our stomachs and giving our taste buds something to chew on.

Due to these parallels, addicts and emotional eaters have discovered a unique recovery strategy, in that they can all use the idea of supporting and helping others who struggle with the same issues.



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Treating Fibromyalgia with Painkillers: Effective?

December 13th, 2010
Carmelo Pierce asked:




When a person feels overly exhausted and constantly hurting all over, they may have fibromyalgia. This is a chronic condition characterized by widespread pain in the muscles, ligaments, and tendons of a person, as well as fatigue and multiple tender points. These points are places in a person’s body where a slight hint of pressure causes pain. Also called fibrositis, chronic muscle pain syndrome, psychogenic rheumatism and tension myalgias, fibromyalgia is more common to women than men.

People dealing with this condition often report that they do not respond to the types of medication that relieve other people’s pain. A new research from Michigan explains that this might be because patients with fibromyalgia were found to have a reduction in the binding ability of a type of receptor in the brain that is the target of opioid painkiller drugs such as morphine. The study includes PET scans (Positron Emission Tomography) of the brains of patients with fibromyalgia, and an equal number of people without the said condition. Results indicate that the patients with fibromyalgia have reduced their mu-opioid receptor (MOR) availability within the parts of the brain that normally process and dampen pain signals, specifically the nucleus accumbens, anterior cingulate and the amygdala. According to one of the research investigators, the reduced availability of the receptor was closely associated with greater pain for people with fibromyalgia. He said that these findings could explain why opioids are anecdotally thought to be ineffective for people with fibromyalgia. He also added that this particular finding is significant because it has been hard to determine the cause of pain in patients with the said condition, to the point that acceptance of the condition by medical practitioners were slow.

Opioid pain killers work by binding to opioid receptors in the brain and spinal cord. In addition to morphine, they include codeine, medications like Darvocet, Vicodin and Oxycontin. Researchers in this study theorized from their findings that with the lower availability of the MORs in three regions of the brain of people with fibromyalgia, such opioid based pain killers may not be able to bind as well to the receptors as they can in the brains of those people without the condition. To make it more simple, when the pain killers cannot bind to the receptors, they cannot relieve the patient’s pain as effectively. The reduced availability could result from a reduced number of opioid receptors, enhanced release of endogenous opioids, or both.

The research also found a possible link with depression. The PET scans showed that fibromyalgia patients with more depressive symptoms had reductions of MOR binding potential in the amygdala, a region of the brain thought to adjust mood and the emotional dimension of pain.

In knowing this, people should be more aware of their body and how it reacts to pain. Fibromyalgia is a condition where the intensity of symptoms actually vary. It is best if people are informed of this condition, specifically, that this health problem is not progressive nor life threatening. Self-care can  help reduce fibromyalgia’s symptoms by getting enough sleep, exercising regularly, and maintaining a healthy lifestyle.



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