Archive for the ‘ultram’ category

Can anyone tell me if there is a chemical difference between the tramadol for a dog and for a person?

March 24th, 2011
Nancye1962 asked:


I am trying to find out if there is a chemical difference between the 50 mg tramadol prescribed by a vet for a 46 pound dog, and the 50 mg tramadol prescribed for a human. If there is, what is the chemical difference?
I appreciate the answers. I have so old tramadol that was precscribed for me, and was wondering if it would hurt my dog. I have a beagle, and I’m fairly sure now that it’s his back that’s hurting him, (vet ruled out everything else) and he had given the dog tramadol, but he’s out now- so I was wondering if I could give him what I had left from my own medicine (not out of date yet). Didn’t want to risk unless had more than one opinion. I can also call the vet tomorrow and double check too. Thanks!

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The noble analgesic

March 15th, 2011
John Scott asked:




Pain is the most undesirable feeling people usually experience. And even though no one really wishes to experience it, they just can not escape this feeling. The only thing that brings people to the physicians is pain. Mostly, people visit the doctor for getting relief from pain because of different reasons. Pain might differ from moderate to severe, according to the origin and severity degree of the origin. Some pain might be a natural part of life. It may need taking care to handle and get relief. Some times your pain might be so bad and strong, that it becomes truly hard to handle and manage. In such cases, the only solution to problem is taking a very strong painkiller. Pain extirpating and management is an inherent thing for possessing and at fully enjoying the healthy life without needless sufferings. Pain effects are only negative for living. They retard mental stamina, body strength, general health and our overall peace. To get immediate ease from the pain we are usually using some treatments, such as painkillers, exercises and meditation. While some painkillers might bring alternative harmful side effects, people are still going for this option frequently as it brings prompt solution. They go for pain reducing medicaments such as Tramadol. This treatment is an efficacious painkiller, with a method of action pretty much identical to those of the drugs (narcotics). It is the generic formulation of a painkiller known as Ultram. The International Union of Pure and Applied Chemistry (IUPAC) name of this medication is rac-(1R, 2R)-2-(dimethylaminomethyl) -1-(3-methoxyphenyl)-cyclohexanol. It is used for the treatment of moderate to severe pain of different sources. This medicine is the typical synthetic opioid used for treating different kinds of pain. It possesses possible arrangements on the serotonergic, noradrenergic and GABAergic body systems. The medicine is the German Grunenthal GmbH pharmaceutical company’s valiable present to the humankind for pain eradication. This analgesic is also marketed under such trade name as Tramal. It is offered in both intramuscular and intravenous forms, that might be injected respectively to muscles and veins. You can also find it in oral preparations. It is found as Tramadol hydrochloride (hydrochloride salt) which is commerced under Ultram brand name in the United States of America. Another form is Ultracet obtainable right next to acetaminophen. The dosage for consumption differs with pain degree occurred in the patient’s body. It has more or less ten percents of morphine’s effect, when injected by IV/IM channel. Oral dosage varies from 50 to 400 mg daily, sometimes even up to 600 mg daily in certain cases of severe pain. As it is N- and O-demethylated to five separate metabolites, Tramadol endures hepatic metabolism by the way of cytochrome P450 isozyme CYP2D6. The most adverse of its side effects include drowsiness, vomiting, sweating, respiratory depression, and nausea. While many physicians refer this medicine to pain relief, in many cases according to the Ultram’s prescription, Tramadol “may encourage physical and psychological dependence of morphine-type”.



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Should we follow the example of the treatment given to animals?

March 13th, 2011
John Scott asked:




There is a wonderful idiom, several times used as the title to a movie and offering the comparative warning, “It shouldn’t happen to a dog.” It refers to some proposed act or omission that is so unpleasant to humans, it should not even be wished on a dog (being a mere animal, it might be expected to bear most things, but not this). Human culture has grown up with animals a part of our lives. Whether as pets, living as one of the family in our own homes, or as working beasts, we value them for “who” they are and what they can do for us. This means treating them in much the same way as humans. If they get sick, we give them our medications. Sometimes, they retaliate by acting as incubators to encourage viruses to mutate and, as with “swine” or “bird” flu, return the favor by passing us infections to which we have no resistance. But, in general, we worry about them. Even the animals we propose to eat are stuffed full of antibiotics to keep them fit and healthy. So, keeping this real, there are many protections we have put in place for our animals. The most carefully monitored rules affect horses. These powerful animals have become a key part of the gambling industry, running in races for our excitement and jumping fences for our admiration. As with most sports, the fear is that horses dosed with stimulants and other drugs might run faster and/or jump higher. Think Barry Bonds and the debate about the use of steroids in Major League Baseball for an understanding of the passion in the world of racing and equestrian sports. At the top of the sport, the International Equestrian Federation (FEI) carried out detailed research in the early part of this century and concluded it was unsafe to allow horses to compete if they were relying on painkillers. In 2004, the Federation moved toward a zero-tolerance policy. This was approved by the Veterinary Committee and representatives of the different national bodies. The risk of seriously injuring the horses was too great and this protective care was strongly endorsed by horse-lovers around the world. Horses should only be used when they are completely fit. It’s therefore somewhat surprising to see the FEI change the policy to allow the use of a range of painkillers. Indeed, the decision has provoked outrage. Yet, when it comes to humans, we routinely buy tramadol, dose ourselves and then carry on with sometimes energetic activities. The problem is the same as with horses. With pain suppressed, we can attempt to move normally and aggravate the existing injuries. As with everything, a balance has to be struck. Pain is inconvenient most of the time but nevertheless a useful warning when we might be overexerting ourselves. When we are recovering from injuries or learning to live within new physical limits, using tramadol is reasonable in the first stages of regaining mobility. But, in the long term, it’s better to recover muscle tone and build stamina without the help of drugs. That way, we learn coping strategies and need only use a painkiller when the pain flares up again. We are entitled to the same protection as horses.



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